I wouldn't exactly call this a reliable source but maybe actor Rob Lowe knows something that everybody else maybe even Peyton Manning doesn't know. Lowe says that  Peyton will be hanging up the pads and retire according to his twitter page

I highly doubt we can trust this as a source but a few years back we said the same thing about TMZ and look how much news we get from them these days. If this does happen to be true, maybe Lowe will have a new career working for ESPN or maybe the NFL Network.