The Tom Izzo led Michigan State Spartans are the lone #7 seed and the only team not ranked as a #1 seed in the Final Four.  So far, the slipper resides with the Spartans this tournament as they already upset #2 seeded Virginia and #4 seed Louisville.

Michigan State now faces perhaps their toughest test yet as they prepare for a matchup against the top seed out of the south region, Duke.

Duke head coach Mike Krzyzewski is 8-1 all-time against Tom Izzo, and Duke beat Michigan State 81-78 back in November.

So what might it take for the Spartans to pull off the upset over the heavily favored Duke team?  Dick Vitale joined Armen and Levack to break down the chances Michigan State can win.

"I think the big decision is what do they do?  How do they play Okafor?  Do they decide to double him up?  Do they try to play him one-on-one and try to shut out the perimeter players like Notre Dame when they played Duke," Vitale said, "I would try to lock up the guards basically try to lock up the guards when you look at Cook and certainly Tyus Jones, they can shoot the three and you factor in Matt Jones now, and Winslow who is that 'X-factor', he's a star, he has been absolutely brilliant this tournament."

Should Michigan State match up against Okafor with only one man, the ACC player of the year might have a special night.

"Duke is gonna score," Vital said, "They got a very good offensive team and they have to do a really good job trying to contain that perimeter game."